Xeomin: What is German Xeomin?

Xeomin is a type of wrinkle-reducing agent known as Botulinum toxin, manufactured by MERZ PHARMA GMBH & CO. KGaA, a German company. It is imported and distributed by Merz Aesthetics Thailand.

Currently, there are various wrinkle-reducing agents available in Thailand, including Allergan from the United States and Dysport from England and Korea.

Xeomin has become popular due to its high purity, lack of impurities, and small molecule size, which provides a natural appearance. It is also an option for individuals who may have developed resistance to other Botulinum toxins.
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Common Injection Sites for German Xeomin

German Xeomin is effective in distributing the medication evenly after injection, resulting in a comfortable, natural facial expression. It is commonly used for correcting wrinkles and lifting facial contours. Moreover, it can be injected into various areas, similar to other Botulinum toxin brands, including:

• Forehead wrinkles
• Glabellar lines (wrinkles between the eyebrows)
• Crow’s feet wrinkles
• Periorbital lines (small wrinkles under the eyes)
• Facial reshaping or contouring
• Reduction of jaw size
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Advantages of German Xeomin

Manufactured with XTRACT Technology™, a process that eliminates unnecessary proteins, ensuring high purity and the absence of foreign substances. Small molecule size (Low Molecular Weight) allows for effective drug distribution, resulting in a natural-looking appearance. Suitable for cases of Botulinum toxin resistance, with research supporting its efficacy in resistant cases. Fast onset of action, with visible results within 3 days. Long-lasting results lasting 4-6 months. (Individual results may vary, and post-injection self-care is important.)

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Understanding Botulinum Toxin Resistance

Botulinum toxin resistance occurs when the body produces antibodies against Botulinum toxin, recognizing it as a foreign substance. This can happen with the administration of non-standardized or excessive amounts of Botulinum toxin.

Initially, even with counterfeit or non-standardized Botulinum toxin, noticeable results may occur due to the body’s initial confusion in identifying the foreign substance. However, subsequent injections can lead to antibody production, resulting in reduced effectiveness or minimal results, even with genuine Botulinum toxin brands.
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Recognizing Botulinum Toxin Resistance

The duration of Botulinum toxin efficacy decreases over time, typically from 6 months to 4 months, then to 3 months, until injections no longer have an effect. Alternatively, resistance can be assessed by injecting one side of the forehead or a wrinkle-prone area and observing the results after 2 weeks. Persistent wrinkles indicate Botulinum toxin resistance. Additionally, resistance can be confirmed through testing.
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Preventing Botulinum Toxin Resistance

Choose standardized products with high purity to prevent antibody formation. Avoid non-standardized brands or those with high protein impurities, as they can trigger antibody production. Use appropriate injection volumes to avoid over-injection or excessive frequency, which can contribute to resistance. Select experienced and knowledgeable physicians for injections, as they can accurately assess facial expressions and dosage requirements.
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Identifying Genuine German Xeomin

Scan the QR code on the box for verification. Check the list of clinics using genuine products on www.merzaesthetics.co.th. Ensure that the batch number under the box matches that under the bottle, and Verify the registration number. The bottle should be vacuum-sealed.